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Single-step purification of human C4b-binding protein (C4BP) by affinity chromatography on a peptide derived from a streptococcal surface protein.

Many Gram-positive bacteria express surface proteins that bind human plasma proteins. These bacterial proteins, and derivatives of them, are of interest for analysis of bacterial pathogenesis and as immunochemical tools. Well-characterized examples include the IgG-binding reagents staphylococcal protein A and streptococcal protein G, and the recently described streptococcal IgA-binding peptide Sap

Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age

A diminished capacity to maintain tissue homeostasis is a central physiological characteristic of ageing. As stem cells regulate tissue homeostasis, depletion of stem cell reserves and/or diminished stem cell function have been postulated to contribute to ageing. It has further been suggested that accumulated DNA damage could be a principal mechanism underlying age-dependent stem cell decline. We

Effects of Sunlight on Organic Matter and Bacteria in Lakes

This thesis examines the role of sunlight, specifically ultraviolet-B radiation (280-320 nm), on dissolved organic matter (DOM) and bacteria in lakes. Field experiments in lakes with different humic contents and geographical locations have been performed. Photooxidation result in that part of DOM is oxidized to inorganic carbon (DIC), mainly CO2. The photooxidation rate can be of the same magnitu

Water Erosion Modelling using Fractal Rainfall Disaggregation, a Study in Semiarid Tunisia

In the Tunisian semiarid area, water erosion processes have led to negative economic and environmental consequences in a context of limited water resources. To characterize and predict these degradation phenomena, a comprehensive high-resolution data base on erosive rainfall, together with siltation records for 28 small reservoirs were analyzed. The studied small reservoir network displays a gener

Shaping nursing home mealtimes

A number of studies stress the importance of positive mealtime experiences for nursing home residents. However, the components that comprise an ideal nursing home meal remain unclear, reflecting the ambiguity of whether nursing homes should be framed as institutions, domestic settings or a type of hotel. In this study, nursing home meals were viewed as situations that the involved parties could co

Effects of chronic citalopram treatment on central and peripheral spontaneous open-field behaviours in rats

The spontaneous open-field behavioural effects of 10 days of chronic treatment with two clinical doses (10 and 20 mg/kg daily) and one high/toxic dose (100 mg/kg daily) of the selective serotonin reuptake inhibitor citalopram (delivered subcutaneously by implanted osmotic pumps) were examined in rats. Central and peripheral arena locomotor and rearing activities were recorded simultaneously, and t

Doppler interference in dissociative resonant photoemission

Resonant photoemission involving dissociative core excited states has been the subject of a great number of experimental and theoretical investigations in recent time. The resonant decay of such dissociating systems has been shown to lead to semiatomic Auger electron emission spectra, with particular angular behavior. In the present paper a detailed theoretical analysis of dissociative resonant ph

Coxsackievirus and adenovirus receptor expression in non-malignant lung tissues and clinical lung cancers

Adenoviral vector mediated gene delivery has been applied in clinical trials and mechanistic studies to explore new treatment approaches for lung cancers. The expression of coxsackievirus adenovirus receptor (CAR), the primary receptor for the most commonly used adenovirus serotype 5 (Ad5)-based vectors, predominantly determines the permissiveness of lung cancer cells. CAR expression is also sugge

Population size and genetic diversity in sand lizards (Lacerta agilis) and adders (Vipera berus)

Because low genetic diversity may threaten the viability of isolated populations, conservation biologists have devoted much effort to quantify genetic variation. Two techniques routinely used involve levels of mini- and microsatellite polymorphism, with the assumption that levels of variation at these parts of the genome will be reflected in levels of variation at other loci. Our data challenge th

Ovarian cancer linked to lynch syndrome typically presents as early-onset, non-serous epithelial tumors

Objective. Heredity is a major cause of ovarian cancer and during recent years the contribution from germline mismatch repair (MMR) gene mutations linked to Lynch syndrome has gradually been recognized. Methods. We characterized clinical features, tumor morphology and mismatch repair defects in all ovarian cancers identified in Swedish and Danish Lynch syndrome families. Results. In total, 63 epit

Barn som bevittnat våld i nära relation - brottsoffer, men inte målsägande

I Sverige har inte barn som bevittnat våld i nära relation målsägandestatus, d.v.s. straffrättslig status som brottsoffer, något som kritiserats av FN:s barnkommitté. Ett barn som har bevittnat våld i nära relation ses med dagens svenska reglering däremot som ett brottsoffer i ordets vida betydelse. Detta genom att barnet sedan 2006 har möjlighet att ansöka om s.k. bevittnandeersättning från BrOM.

False promise or promise with a fault : deciphering the effectiveness of eco-label governance in the german textile market

An understanding of the inherent effectiveness-potential of environmental product-labels is important because of the growing presence of these labels as governance regimes, especially in the textile market. The proper governance of eco-labels has the potential to assist with the transformation to more environmentally friendly consumption, but not enough is known about the inherent qualities that m

Evaluating VaR and ES for commodities - both conventionally and with neural networks

As commodities are becoming more popular and accessible assets for speculative and hedging purposes, the limited research regarding risk management for said asset-class justifies further contribution to the deficient output. Many previous studies have highlighted the extraordinary high volatility, with non-linear and clustering characteristics associated with commodities. Hence, incorporating vola

Side Streams Throughout the Food Supply Chain in Västra Götaland - A Study of Reported Data, Interviews with Food Producers and a Simplified LCA Case Study

Vikten av resurseffektivitet i livsmedelskedjan är tydlig, eftersom denna sektor är en av de största bidragarna till negativ klimatpåverkan globalt. Målet med den här uppsatsen var att utforska sidoströmmar av mat inom livsmedelskedjan i Västra Götaland, för att kartlägga hur mycket som redan är täckt i statistiken och vilka luckor i datamaterialet som finns för framtida forskning att täcka. DessThe importance of resource efficiency in the food supply chain is clear, since this sector is one of the biggest contributors to the negative environmental impacts globally. This thesis project aimed to examine food side streams throughout the food supply chain in Västra Götaland, to map out how much has already been covered statistically and what gaps there are in the data for future research to

Remittances and Household Expenditure in Jamaica

More than 50 percent of Jamaican households are remittances receiving. Remittances generally form a source of supplemental household income by helping households cover expenses such as utilities,healthcare, education etc. Studies have focused on its reaction to economic shocks, structural changes, its use as insurance or safety net or generally just observing trends. This study employs propensity

Benefits of Multi-Echelon Inventory Control

I ABSTRACT This thesis studies a two-echelon distribution inventory system with a central depot which supplies N non-identical retailers with a single product. Stochastic customer demand occurs solely at the retailers. The purpose of the master thesis project is to evaluate the potential benefit of two methods in which the control of the inventory points in the inventory system is coordinated. The