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Recovery of cognitive and emotional functioning following withdrawal of topiramate maintenance therapy
The present investigation reports cognitive improvement following withdrawal of topiramate (TPM) maintenance therapy in two patients with intractable seizures. The first patient received a neuropsychological evaluation after 10 months of adjunctive TPM treatment and was reassessed after complete withdrawal. The second patient received a first evaluation without TPM therapy. A reassessment was cond
Investigation of binding event perturbations caused by elevated QCM-D oscillation amplitude
We report measurements with the quartz crystal microbalance with dissipation monitoring (QCM-D) technique, with focus on how the shear oscillation amplitude of the sensor surface influences biorecognition binding events. Technically, this is made as reported recently ( M. Edvardsson, M. Rodahl, B. Kasemo, F. Hook, Anal. Chem., 2005, 77( 15), 4918-4926) by operating the QCM in dual frequency mode;
Safety as a key performance indicator: Creating a safety culture for enhanced passenger safety, comfort, and accessibility
Modal shift from private cars to high quality public transport is often seen as a means for improved traffic safety while simultaneously achieving other policy goals. This paper aims to describe safety from a travel-chain perspective and suggests an approach for using accident data as performance indicators. Findings from a recent Swedish case study of bus accidents show that the number of unrepor
Spatial variability linking carbon resource heterogeneity and microorganisms; causes and consequences
Popular Abstract in Swedish Organiskt kol och mikroorganismer har ofta en mycket hög spatiell variation i jorden. Dessutom är mikroorganismer ofta begränsade av mängden kol även om detta beror på den den relativa koncentrationen av kväve, fosfor och organiskt kol i systemet. Man kan dock anta att mikroorganismers biomassa och aktivitet kan samvariera med halten organiskt kol i jordar som har en föOrganic carbon and bacteria have a high variability at different scales in the soil, and organic carbon may be a limiting factor for growth of soil bacteria. Thus, it can be expected that these co-vary at different scales in the soil. In this thesis, I have studied the spatial interaction between soil bacteria and natural and contaminant (polycyclic aromatic hydrocarbon, PAH) organic carbon. The o
Ultrafast Dynamics in Ground and Excited States of Porphyrin Molecules
This thesis describes inter and intramolecular dynamics in porphyrin molecules. To create a basis for understanding the energy and electron transfer processes in photosynthesis, the ultrafast dynamics of monomeric chlorophyll a, chlorophyll b and bacteriochlorophyll a were studied with ultrashort laser pulses. The transient absorption spectra of all three molecules were found to have pronounced co
Smoking and obesity associated BDNF gene variance predicts total and cardiovascular mortality in smokers.
OBJECTIVE: The brain derived neurotrophic factor (BDNF) locus has been implicated in psychiatric and substance related disorders. Recent genome-wide association studies (GWAS) have shown strong associations between single nucleotide polymorphisms in BDNF, smoking behaviour and high body mass index (BMI). Our aim was to test whether genetic BDNF variation alters the risk of smoking related morbidit
A palaeomagnetic and Ar-40/Ar-39 study of mafic dykes in southern Sweden: A new Early Neoproterozoic key-pole for the Baltic Shield and implications for Sveconorwegian and Grenville loops
We present the results of palaeomagnetic and Ar-40/Ar-39 studies of the Proterozoic mafic dykes in the Norrkoping and Falun areas of the southern Sweden. The primary remanence of two 939 +/- 3 Ma dykes is supported by the rigorous baked contact test. The remanence direction of two other dykes, one of which was previously U-Pb dated at 946 +/- 1 Ma is close to the reverse direction of 939 Ma dykes.
Mass transport of contaminated soil released into surface water by landslides (Göta River, SW Sweden)
Landslides of contaminated soil into surface water represent an overlooked exposure pathway that has not been addressed properly in existing risk analysis for landslide hazard, contaminated land, or river basin management. A landslide of contaminated soil into surface water implies an instantaneous exposure of the water to the soil, dramatically changing the prerequisites for the mobilisation and
PRODUCT IDENTIFICATION SYSTEMS FOR CONSTRUCTION AND FACILITY MANAGEMENT
This paper presents a state-of-the-art analysis of current systems for product identification utilized within the Swedish sector of construction and facility management. The study also discusses the concept of object and class identification in information systems development. The purpose of the study is to identify and define concepts in a common information structure that provides a framework fo
Sediment pigments as biomarkers of environmental change
This thesis demonstrates the usefulness of sedimentary pigments as biomarkers of environmental change in estuarine systems and as biomarkers in lakes in relation to climate change. These are two fields where sediment pigment records as measured by high-performance liquid chromatography (HPLC) are emerging areas of study. A detailed study was undertaken to examine the effects of different storage o
On the Use of Ultrasound Phase Data for Arterial Characterization
Popular Abstract in Swedish Hjärt- och kärlsjukdomar som till exempel åderförkalkning utgör en av världens vanligaste dödsorsaker. I den här avhandlingen har vi utvecklat olika metoder som med hjälp av bildanalys ger värdefull information om kärlväggen i syfte att förbättra kunskapen om artärer och framförallt åderförkalkning. I avhandlingen presenteras fem olika metoder som alla är baserade på biAtherosclerosis is one of the major causes of death in the world. It is an inflammatory disease in the arteries which causes a gradual increase in arterial wall thickness and stiffness. Eventually a plaque could be formed, protruding into the artery and partially occluding the blood flow. Rupture of such a plaque could cause cardiac infarction or stroke. This dissertation revolves around finding b
Växandets gestaltning i Peter Pohls romansvit om Micke
Popular Abstract in Swedish "Växandets gestaltning i Peter Pohls romansvit om Micke" behandlar barndomsskildringarna "Regnbågen har bara åtta färger" (1986) och "Medan regnbågen bleknar" (1989) samt ungdomsromanerna "Vilja växa" (1994), "Vi kallar honom Anna" (1987) och "Klara papper är ett måste" (1998). Till sviten förbinds sagor ur "De Stora Penslarnas Lek" (1989) och dikter ur "Minns det" (199Peter Pohl was born in Germany in 1940 but grew up in Stockholm, a setting reflected in many of his books. Pohl, a researcher at the Royal Technical University in Stockholm, made his fiction debut with the multi-prize-winning novel "Janne, min vän" (1985), and is internationally acclaimed for, among other things, the way in which his teenage novels highlight existential questions. The purpose of t
Can I be an Instantaneous Stage and yet Persist Through Time?
Computerised Three-Dimensional Analysis of Optic Nerve Head Topography in Normal and Glaucomatous Eyes
Evaluation of the optic nerve head topography is one of the most important methods to diagnose and monitor patients with glaucoma. Until recently, optic nerve head topography has most often been judged by either ophthalmoscopy or from optic disc photographs. These methods are subjective and examiners do not have access to absolute measurements of the optic disc size and cup depth. The result of su
Clostridium lundense sp nov., a novel anaerobic lipolytic bacterium isolated from bovine rumen
A strictly anaerobic, mesophilic, endospore-forming, lipolytic bacterium, designated strain R1(T), was isolated from bovine rumen fluid and characterized. Cells of this isolate were Gram-positive, non-motile rods that formed spherical terminal spores. The overall biochemical and physiological characteristics indicated that this strain should be placed in the genus Clostridium. The strain grew at t
Quantitative morphology of stimulation-induced damage in rabbit fast-twitch skeletal muscles
The purpose of this study was to examine the contention that stimulation-induced damage, resulting in degeneration with subsequent regeneration, plays a major role in the transformation of fibre type brought about by chronic electrical stimulation. Data from histological and histochemical sections of 9-day-stimulated rabbit fast-twitch muscles were analysed with multivariate statistical techniques
Additive and non-additive genetic architecture of two different-sized populations of Scabiosa canescens
Reduction of decomposition rates of Scots pine needle litter due to heavy-metal pollution
Decomposition of unpolluted Scots pine needle litter was studied in two heavy-metal-pollution gradients in Sweden; one near a brass mill and the other around a primary smelter. In the latter area locally collected polluted Scots pine needle litter was also incubated. Decomposition rates were strongly influenced by the metal pollution and a decrease in the rate of mass-loss occurred. In the brass-m
Fe II emission spectra in AGN: observations and theoretical interpretation
The enrichment of Fe, relative to alpha elements such as O and Mg, represents a potential means to measure the ages of quasi-stellar object (QSO) host galaxies and probe nucleosynthesis in the early universe. QSOs exhibit prominent Fe II features and Mg II 2800 angstrom resonance doublet emission in the ultraviolet. Although chemical evolutionary models predict that the Fe/Mg abundance ratio decre
