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The effect of hyperthermia and/or nicotinamide (200 mg/kg of body weight) on the tumour growth delay induced by radiation was evaluated in a C3H mouse mammary adenocarcinoma. The study showed a radiosensitizing effect of hyperthermia and of nicotinamide but the combination of all three modalitites showed no increased tumor growth delay compared to hyperthermia and radiation alone. The tumour growt
Myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis (EAE) is an inflammatory disease in rats that closely mimics many clinical and histopathological aspects of multiple sclerosis. Non-MHC quantitative trait loci regulating myelin oligodendrocyte glycoprotein-induced EAE have previously been identified in the EAE-permissive strain, DA, on rat chromosomes 4,10,15, a
Popular Abstract in German Spannungsgesteuerte Kalziumkanäle haben eine große Bedeutung in vielen elektrisch erregbaren Zellen, wie z.B. in Nervenzellen und pankreatischen beta-Zellen. Hier werden sie folgendermaßen aktiviert: In der Nahrung enthaltener Traubenzucker (Glukose) wird nach einer Mahlzeit über den Blutstrom im Körper verteilt und in die beta-Zellen über Glukosetransporter aufgenommen.Voltage-gated Ca2+ channels are essential transducers of cellular signals in many electrically excitable cells. In the pancreatic beta-cell they mediate controlled Ca2+ influx, which is the final trigger for Ca2+ dependent release (exocytosis) of the blood glucose lowering hormone insulin. Several subtypes of voltage-gated Ca2+ channels are known and the L-type has been found to be the main contri
Popular Abstract in Swedish När yrkesutbildningar teoretiseras ställs lärare och studerande inför skriftspråksbaserad, ofta abstrakt information som de förväntas läsa, kritiskt granska, ifrågasätta och omskapa till något eget. Språk och lärande hör nära samman, men när de studerandes vardagsspråk ska möta sådana texter kan språkandet skapa problem. Vårt sociala sammanhang har stor betydelse för vaBrandvägg describes how a group of firefighters, who consistently maintain that they are “practitioners and not theorists”, relate to various forms of language based knowledge and language based “knowledging” in their vocational training, which is based on problem based learning. From a sociocultural perspective to learning, and within the parameters of a didactic perspective with the focus on the
In many developing tropical countries, rapid urban growth leads to several problems, including increased thermal stress. This has negative consequences for people's health and well-being, and affects social and commercial outdoor activities negatively. Consequently, the creation of thermally comfortable microclimates in urban environments is highly important. The main aim of this thesis is to dee
Diamond-Blackfan anemia (DBA) is a congenital erythroid aplasia that usually presents as macrocytic anemia during infancy. Linkage analysis suggests that at least four genes are associated with DBA of which two have been identified so far. The known DBA genes encode the ribosomal proteins S19 and S24 accounting for 25% and 2% of the patients respectively. This study shows that RPS19 gene transfer
The light response of a BGO crystal has been measured for particles Z = 1-8, A = 1-16 in the energy range similar to2-60 A MeV. The reaction products are identified by a DeltaE(Si) - E(Sci/PD) telescope, The position of the jump in the value of the signal from the PD at the punch-through points is used to calibrate both the DeltaE(Si) and E(Sci/PD) scales in MeV. The dependence of the light output
Secretion of outer membrane vesicles (OMV) is an intriguing phenomenon of Gram-negative bacteria and has been suggested to play a role as virulence factors. The respiratory pathogens Moraxella catarrhalis reside in tonsils adjacent to B cells, and we have previously shown that M. catarrhalis induce a T cell independent B cell response by the immunoglobulin (Ig) D-binding superantigen MID. Here we
Genetic and environmental factors, including the commensal microbiota, have a crucial role in the development of inflammatory bowel disease. Aberrant activation of the transcription factor NF-κB is associated with chronic intestinal inflammation in mice and humans. Recently, an emerging family of innate lymphoid cells (ILCs) has been identified at mucosal sites contributing to the maintenance of g
Popular Abstract in Swedish Min forskning handlar om hur nedbrytningen av fett i fettceller regleras genom att fosfat tas av och sätts fast på olika proteiner inuti fettcellerna. För att man skall förstå hur fettnedbrytning hänger ihop med att fosfat reagerar med proteiner är det bra att veta något om hur fettcellernas ämnesomsättning regleras. Energilagring och fettomsättning Människokroppen laAdipose tissue is the main site of energy storage of the body and an important endocrine organ. Knowledge of the regulation of fat metabolism and the endocrine factors secreted by the adipocyte is crucial for the understanding of diseases such as obesity and diabetes. Insulin is the main antilipolytic hormone. Protein kinase B (PKB) and phosphodiesterase 3B (PDE3B) are both phosphorylated and acti
Popular Abstract in Swedish Så gott som alla djur i naturen utgör ett potentiellt byte för rovdjur. Bokstavligt talat är det därför livsviktigt att försöka undvika att bli upptäckt och fångad av sina naturliga fiender. Då olika arter exponeras för olika typer av rovdjur (predatorer) är det kanske inte så konstigt att det finns en enorm variation av försvarsstrategier i naturen. Mer förvånande är kPredation imposes a potent evolutionary force on prey, moulding the evolution of traits and diversification of species, and can furthermore have powerful ecological consequences. We know that different species vary in how they cope with their natural enemies, and, consequently, a huge range of anti-predator defences are displayed in nature. Yet there is a growing recognition that, if we zoom into
Popular Abstract in Swedish Populärvetenskaplig sammanfattning (Popularised summary in Swedish) Beta-microseminoprotein är ett äggviteämne (protein) som först hittades i sädesvätska (seminalplasma). Det är inte känt vad det har för funktion. Man känner i dag inte till någon som har brist på Beta-microseminoprotein eller någon sjukdom som beror på Beta-microseminoprotein. Den genetiska arvsmassan Human Beta-microseminoprotein is a 94 amino acid protein with 10 cysteins present in seminal plasma and on many mucosal surfaces in the body. The function of the protein is unknown. The purpose of this investigation was to study the distribution of Beta-microseminoprotein in the human body, especially in the stomach. The latter was studied under both normal and pathological conditions. A radioimmu
Relief Aid in East Africa Over a period of six months during second half of 2011, the global humanitarian Community responded to one of the most severe droughts the world has ever seen. A total of 13 million people were given emergency assistance including food, water and shelter. Unfortunately, this intervention is not an isolated event. The countries located in East Africa have a dire history of
Popular Abstract in Swedish Hoppet väcks för sömnsjuka Det sticker till i benet. Du viftar med handen, men alltför långsamt. Du ser en glimt av den ljusbruna flugan, stor som ett bi, och hör hur den surrar vidare genom den varma afrikanska eftermiddagen mot sitt nästa blodmål. Tsetseflugans bett kliar. Inom ett par dagar har det förvandlats till en arg röd svullnad. Därinne förökar sig parasiternIn the last decade, powerful communication and information technology in the form of the mobile phone has been put into the hands of more than 50% of the global population. In stark contrast, a lack of access to medical diagnostic technology with which to diagnose both communicable and non-communicable diseases will mean that many of these people will die of easily treatable conditions. Small, por
During evolution of land plants, a specific motif occurred in the N-terminal domain of the chloroplast-localized small heat shock protein, Hsp21: a sequence with highly conserved methionines, which is predicted to form an amphipathic -helix with the methionines situated along one side. The functional role of these conserved methionines is not understood. We have found previously that treatment, wh
It has been proposed that hyaluronan-binding proteoglycans play an important role as guiding cues during neural crest (NC) cell migration, but their precise function has not been elucidated. In this study, we examine the distribution, structure and putative role of the two major hyaluronan-binding proteoglycans, PG-M/versicans and aggrecan, during the course of avian NC development. PG-M/versicans
2024-03-04 (rev.) Lathund för ärendehantering i SSC Primula Musikhögskolan i Malmö 2024-03-04 (rev.) Lathund för ärendehantering i Primula Innehållsförteckning Rapportering i Primula ............................................................................................................................... 1 Sjuk/friskanmälan .....................................................................
Microsoft Word - H-guide, september, 2016.docx 1 Guide för handledning och examination av självständigt arbete (uppsats) vid Socialhögskolan, Lunds universitet Mikael Sandgren Oktober 2016 2 Förord Jag har tagit över revideringen av handledarguiden efter Marcus Knutagårds löpande revideringar av Katarina Jacobssons arbete med texten som bygger på hennes återkommande möten med examinatorer och hand
https://www.soch.lu.se/internt/sites/soch.lu.se.internt/files/2023-03/handledarguide%20-%20oktober%202016.pdf - 2026-05-10
1 FÖRUTSÄTTNINGAR INKL. RESURSFÖRDELNING FÖR MEDICINSKA FAKULTETENS VERKSAMHET 2025 Beslutad i Medicinska fakultetsstyrelsen 2024-11-13 2 Del 1 FÖRUTSÄTTNINGAR FÖR MEDICINSKA FAKULTETENS VERKSAMHET 2025 Diarienr STYR 2024/2454 3 Innehåll 1 Inledning ................................................................................................................................... 5 2 Universitetets
https://www.intramed.lu.se/sites/intramed.lu.se/files/2024-11/forutsattn-resursford-medfaks-verksamhet-2025.pdf - 2026-05-10
