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This study evaluates two different natural language processing tech-niques: the normalised co-occurrence (PMI) versus neural networks. Incontrast to most previous studies, the focus is on the context of a propor-tional representation system – Sweden –, where the parties in parliamenttend to form coalitions. We test the models by collecting data from thenational parliament (Swedish Riksdag) and usi
Intraventricular hemorrhage (IVH) in preterm infants disrupts neurogenesis in the subventricular zone (SVZ), a key neurogenic niche, yet no effective treatments exist. This work develops a human SVZ-on-a-chip model to investigate the inflammatory response in IVH and its impact on neurogenesis. Using this platform, this work examines the effects of red blood cell lysate (RBCL) and hemorrhagic cereb
The use of CRISPR-Cas bacterial adaptive immunity system components for targeted DNA changes has opened broad prospects for programmable genome editing of higher organisms. The most widely used gene editors are based on the Cas9 effectors of the type II CRISPR-Cas systems. In complex with guide RNAs, Cas9 proteins are able to directionally introduce double-stranded breaks into DNA regions that are
Primary care professionals are often the first line of support for children and adolescents with tic disorders. However, families often report feeling inadequately supported and perceive a lack of knowledge about tics. Few studies have examined primary care professionals’ perspectives on managing tic disorders. This study explored how these professionals understood and managed tic disorders in a D
Background: The global dairy market is experiencing a massive transition as dairy farming has recently undergone modernization. As a result, the dairy industry needs to improve its operational efficiencies by implementing effective optimization techniques. Conventional and emerging optimization techniques have already gained momentum in the dairy industry. This study’s objective was to explore the
Smart Firefighting is a concept that has emerged within the fire engineering and fire science disciplines in recent years. It can enable informed decision making and improved fire safety. However, its scope, definition, outcomes, and value to emergency management remain unclear. To investigate this, a scoping review and a bibliometric analysis were conducted, following the Preferred Reporting Item
DNA replication relies on precise coordination between proteins, including the sliding clamp proliferating cell nuclear antigen (PCNA), which encircles DNA to interact with key players in replication and repair. While biochemical studies have demonstrated interactions between PCNA and DNA polymerases δ and ε during DNA synthesis, the functional role of the Pol ε–PCNA interaction in vivo, particula
Aim: The aim of this study was to describe the routines for handling mother's own milk and donor human milk in Swedish neonatal care units related to national guidelines. Methods: A web-based survey of 24 of 38 neonatal units and 19 of 28 human milk banks in Sweden. Results: Despite national guidelines, breast milk handling varied widely. All units offered lactation support and free breast pumps d
Objective: To characterize patients with protein-losing enteropathy (PLE) diagnosed before age 18 years within a nationwide Swedish Fontan cohort. Methods: Surgical records and medical charts were reviewed for all patients born after January 1, 1993, who underwent Fontan completion before January 1, 2021. Results: Among 573 reviewed patients, 28 (4.8%) developed PLE. The median time to onset of PL
Denna avhandling undersöker (åter)uppbyggnaden av civilt försvar i Europa efter Rysslands annektering av Krim 2014. Mer specifikt analyserar den befintliga uppfattningar om civilt försvar och hur dessa formas i ett flernivåsammanhang, med fokus på samspelet mellan nationella, regionala och internationella institutioner. Genom ett diskursivt institutionellt perspektiv betonar avhandlingen den dynaThis dissertation examines the (re)emergence of civil defence in Europe in the aftermath of Russia's annexation of Crimea in 2014. More specifically, it investigates the existing conceptions of civil defence and how these are shaped in a multi-level institutional context, focusing on the interplay between national, regional, and international levels. Through the lens of discursive institutionalism
The COVID-19 pandemic disrupted the ‘normality’ of our everyday lives, but it did so in the wake of a series of crises within the capitalist system, which worsened the conditions for a liveable world for many while benefitting only a few. In response to these crises, the contributions in this issue highlight the diverse ways activists continue to organise in the midst of social, political, and eco
A migratory divide is a narrow region in which two populations showing different migratory directions meet and presumably also mate and hybridize. Banding of willow warblers, Phylloscopus trochilus, in Europe has demonstrated a migratory divide latitudinally across central Scandinavia. In autumn, southern birds migrate southwest to tropical West Africa, whereas northern birds migrate southeast to
The results of an initial study of enzymatic catalysis in metastable supersaturated solutions of carbohydrates are presented. It has been shown that such solutions, formed in the presence of small amounts of water and alcohol as plasticizers, are sufficiently stable under ambient conditions to enable enzymatic transformations of substrates. A partial phase diagram for a system consisting of glucos
Background: Respiratory symptoms are common in the general adult population. Increased burden of respiratory symptoms may increase the risk of mortality. We assessed the association between respiratory symptom clusters and mortality. Methods: Participants were derived from two population-based Swedish adult cohorts (N = 63,060). Cluster analysis was performed with Locality Sensitive Hashing (LSH)-
Esophageal lesions are common findings in disorders of the digestive tract in patients living with HIV, the most typical symptoms being odynophagia and/or dysphagia. This article provides a narrative review of the spectrum of esophagitis in patients living with HIV, focusing on fungal, viral, bacterial and non-infectious etiologies, as well as co-infections with viral hepatitis viruses. The articl
BACKGROUND: It is unclear how diabetes and metformin use is associated with survival of esophageal cancer.METHODS: This population-based cohort study included new cases of esophageal cancer reported in Sweden from 2006 to 2018 with follow-up through 2019. Diabetes status and metformin use were analyzed in relation to all-cause and disease-specific mortality using multivariable Cox regression. The
Purpose: Exercise-induced hypohydration exacerbates biomarkers of renal injury, but studies isolating the effects of hypohydration without exercise have produced mixed findings. This study investigated the effects of 24-h severe fluid restriction on biomarkers of renal injury and glucose tolerance. Methods: Fifteen males (age: 27 ± 5 y; BMI: 24.1 ± 3.8 kg/m2) completed two randomised trials, invol
