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Many natural populations experience inbreeding and genetic drift as a consequence of nonrandom mating or low population size. Furthermore, they face environmental challenges that may interact synergistically with deleterious consequences of increased homozygosity and further decrease fitness. Most studies on inbreeding–environment (I-E) interactions use one or two stress levels, whereby the resolu
BACKGROUND: Impaired antiviral interferon expression may be involved in asthma exacerbations commonly caused by rhinovirus infections. Allergy is a known risk factor for viral-induced asthma exacerbation, but little is known whether allergens may affect interferon responses.OBJECTIVE: Our hypothesis is that house dust mite (HDM) impairs viral stimulus-induced antiviral signalling.METHODS: Experime
Human enteroviruses (HEV), especially coxsackievirus serotype B (CVB) and echovirus (E), have been associated with diseases of both the exocrine and endocrine pancreas, but so far evidence on HEV infection in human pancreas has been reported only in islets and ductal cells. This study aimed to investigate the capability of echovirus strains to infect human exocrine and endocrine pancreatic cells.
The capacity of communities to reduce negative impacts of climate change on their lives and livelihoods is a function of socio-economic conditions, infrastructure, government accountability and institutional responsiveness and not the least social capital. Africa’s most densely populated region, the Lake Victoria basin (LVB), home to over 30 million people, is one example of a likely future climat
Numerous protein biomarkers have been analyzed to improve prognostication in non-small cell lung cancer, but have not yet demonstrated sufficient value to be introduced into clinical practice. Here, we aimed to develop and validate a prognostic model for surgically resected non-small cell lung cancer. A biomarker panel was selected based on (1) prognostic association in published literature, (2) p
The membrane-anchoring subunit of Bacillus subtilis succinate:menaquinone reductase is a protein of 202 residues containing two protoheme IX groups with bis-histidine axial ligation. Residues Kis13, His28, His70, His113, and His155 are the possible heme ligands. The transmembrane topology of this cytochrome was analyzed using fusions to alkaline phosphatase. The results support a proposed model wi
Manipulation of starch biosynthesis/degradation and formation of novel molecules in storage organs of plants through genetic engineering is an attractive but technically challenging goal. We report here, for the first time, that starch was degraded and glucose and fructose were produced directly when crushed potato tubers expressing a starch degrading bifunctional gene were heated for 45 minutes a
The debate as to whether Jewishness is a biological trait inherent from an "authentic" "Jewish type" (jüdische Typus) ancestor or a system of beliefs has been raging for over two centuries. While the accumulated biological and anthropological evidence support the latter argument, recent genetic findings, bolstered by the direct-to-consumer genetic industry, purport to identify Jews or quantify one
Det Palestinska Territoriet har sedan 1967 varit ockuperat av Israel. Som följd av ett stort antal oroligheter och protester mot ockupationen har Israel infört restriktioner för rörlighet inom Västbanken och Gaza. Rörligheten är styrd med hjälp av exempelvis vägspärrar och blockerade vägar. År 2002 började Israel bygga en betongmur runt om och inuti Västbanken, trots att det motsätter sig internatThe Palestinian Territory has since 1967 been occupied by Israel. Following a large number of disturbances as protests to the occupation, Israel has imposed mobility restrictions for Palestinians in the West Bank and Gaza. The mobility is regulated by for example checkpoints, roadblocks and earth mounds. In 2002, Israel started to build a concrete wall around and inside the Palestinian Territory o
Populärvetenskaplig sammanfattning: Sedimentära facies och fauna från den sensiluriska Bjärsjölagårdkalkstenen i Skåne. Under den sena delen av silurperioden, för ca 420 miljoner år sedan, låg Sverige söder om ekvatorn och Skåne var täckt av ett grunt, varmt hav. I det här havet, den så kallade Baltiska bassängen, bildades sediment som vi idag återfinner bl.a. i ett gammalt övergivet kalkbrott i BThe late Ludlow Bjärsjölagård Limestone Member comprises a part of the Klinta Formation of the Öved-Ramsåsa Group in Skåne, southern Sweden. The ~25 m thick member was formed during the time of the globally known Lau Event and a major sea-level lowstand in the Baltic Basin. This study describes the sedimentary rocks, and their fossil fauna, of the Bjärsjölagård Limestone Member exposed in the Bjär
To investigate whether factors in the fetal or neonatal period influence the risk of later development of coeliac disease we conducted a population-based register study. The Swedish Medical Birth Register was linked with the Hospital Discharge Register and identified 3392 singleton infants born in the period 1987-97 who developed coeliac disease. Perinatal data for these children were compared wit
Syftet med denna uppsats är att analysera kommunernas lagefterlevnad och om den varierar beroende av vilken politisk majoritet som styr kommunen. Konkret kommer det att ske genom att vi analyserar i vilken utsträckning kommunerna implementerat lagen om kommunala bostadsaktiebolagen, manifesterat som större utdelningar och högre vinstmarginaler. Vi kommer att sätta detta i relation till om kommunerThe purpose of this thesis is to analyze the level of law-abidingness of the Swedish municipalities and if this level differs with political majority. We do this by looking at by which extent they have implemented the law concerning these housing companies. By examining trends on their level of profit margins and dividends. Lastly we put this in relation to whether the municipalities adapt to the
Stalaktiter och andra grottsediment har visat sig vara värdefulla verktyg för klimatrekonstruktioner. Med deras hjälp är det möjligt att rekonstruera förändringar av temperatur och nederbörd tillbaka i tiden. De är även användbara i arida områden där andra sedimenttyper sällan existerar. I den här studien undersöks en stalaktit från ”Al Hota”-grottan i norra Oman med hjälp av en petrografisk underSpeleothems and other cave sediments have proven to be valuable tools for climate reconstructions. They allow to reconstruct the changes of temperatures and precipitation over time even in arid areas where other types of sedimentary archives are scarce or even non-existent. In this study, a speleothem from Al Hota cave in northern Oman is investigated by means of petrographic interpretation and an
Bakgrund: The Tree Theme Method® (TTM) är en behandlingsmetod inom psykiatrisk arbetsterapi som bygger på att klienten uttrycker sin livssituation i bildskapande och livsberättelse. Trädet är en central symbol i bildskapandet. Syfte: Studiens syfte var att undersöka hur personer med psykisk ohälsa upplever TTM som behandlingsmetod, främst avseende metodens värde och mening. ValMO-modellen använde
Popular Abstract in Swedish I början av 1980-talet rökte ungefär var tredje gravid kvinna i Sverige. Detta innebar att rökning under graviditet var lika vanligt förekommande som rökning bland den vuxna befolkningen i övrigt. Sedan dess har rökningen bland gravida minskat markant och idag är det ungefär 10-12% som röker vid inskrivningen på mödravårdscentralen. Rökning under graviditet är en av deA smoking cessation program targeting pregnant women and their partners was monitored during 17 years and subjected to several substudies. All women in Blekinge, who gave birth in the months of September during the period 1984 to 2000, were asked to fill out a questionnaire, anonymously, about their smoking habits before and during pregnancy. During these years a long-term educational programme co
The primary aim of the study was to identify inflammatory markers relevant for osteoarthritis (OA)-related systemic (plasma) and local (synovial fluid, SF) inflammation. From this, we looked for inflammatory markers that coincided with the increased amount of O-linked Tn antigen (GalNAcα1-Ser/Thr) glycan on SF lubricin. Inflammatory markers in plasma and SF in OA patients and controls were measure
Elaborating on conceptualizations of kitsch in the realm of art and sociology in the context of ISIS propaganda and culture, this article introduces the concept of jihadi kitsch. Kitsch is characterized by a compulsion to escape from the banality of daily reality and lack of coherent meaning in modern society through, in the words of the philosopher and sociologist Theodor Adorno, a self-made and
